Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors
نویسندگان
چکیده
منابع مشابه
Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors
Metabolic stress occurs frequently in tumors and in normal tissues undergoing transient ischemia. Nutrient deprivation triggers, among many potential cell death-inducing pathways, an endoplasmic reticulum (ER) stress response with the induction of the integrated stress response transcription factor ATF4. However, how this results in cell death remains unknown. Here we show that glucose deprivat...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2017
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.00479-16